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Emoxypine Succinate

CAS No. 127464-43-1

Emoxypine Succinate( —— )

Catalog No. M21129 CAS No. 127464-43-1

Emoxypine Succinate is an antioxidant.?

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    Emoxypine Succinate
  • Note
    Research use only, not for human use.
  • Brief Description
    Emoxypine Succinate is an antioxidant.?
  • Description
    Emoxypine Succinate is an antioxidant.?(In Vitro):Emoxypine succinate shows reactive oxygen species overproduction and disruption of the mitochondrial inner membrane due to the decreasing of transmembrane potential.(In Vivo):Emoxypine succinate (i.p.; 40 mg/kg; 1 time per day, 14 days) decreases the production of reactive oxygen species, mitochondrial transmembrane potential percentage of leukocyte and the percentage of FITC Annexin V- positive cells of leukocyte suspension.
  • In Vitro
    Emoxypine succinate shows reactive oxygen species overproduction and disruption of the mitochondrial inner membrane due to the decreasing of transmembrane potential.
  • In Vivo
    Emoxypine succinate (i.p.; 40 mg/kg; 1 time per day, 14 days) decreases the production of reactive oxygen species, mitochondrial transmembrane potential percentage of leukocyte and the percentage of FITC Annexin V- positive cells of leukocyte suspension. Animal Model:Rats Dosage:40 mg/kg Administration:Intraperitoneal, 1 time per day, 14 days Result:Significantly increased the percentage of Annexin V-positive cells, reduced the apoptotic percentage of white blood cells and decreased the production of reactive oxygen species by leukocytes.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    others
  • Research Area
    Cardiovascular Disease
  • Indication
    Ischemic Stroke

Chemical Information

  • CAS Number
    127464-43-1
  • Formula Weight
    255.27
  • Molecular Formula
    C8H11NO.C4H6O4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?H2O : 250 mg/mL (979.36 mM)
  • SMILES
    CCc1nc(C)ccc1O.O=C(O)CCC(=O)O
  • Chemical Name
    2-Ethyl-6-methylpyridin-3-ol Succinate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Pashin E N Shvedova A A . [The effect of the synthetic antioxidant emoxypine on the tonus of the coronary vessels][J]. farmakologiia i toksikologiia 1989 52(5):17-19.
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